Vitamin D status in children and adolescents with type 2 diabetes in a sun-rich environment

CellR4 2016; 4 (6): e2214

  Topic: Diabetes     Category:

Abstract

Background: In obese children, hypovitaminosis D has been found to be associated with common risk factors for type 2 diabetes including abnormal fasting insulin, glucose and hemoglobin A1c. Adult type 2 diabetics have a lower vitamin D levels but this has not been documented in children/adolescents who reside in a sun-rich environment.

Objective: The purpose of this study was to estimate the prevalence of vitamin D insufficiency/deficiency in children with type 2 diabetes in a sun-rich environment.

Materials and Methods: Children (N = 48) diagnosed with type 2 diabetes who had serum 25-hydroxyvitamin D level data available from a clinical visit (2008-2012). Results were obtained from a retrospective chart review. Vitamin D deficiency was defined as 25-hydroxyvitamin D level ≤ 50 nmol/L and insufficiency ≤ 75 nmol/L. Obesity was defined as body mass index (BMI) >95% and overweight as BMI >85- <95% for age and sex.

Results: The majority of the population was non-Hispanic black (73%), followed by 22% Hispanic, and 4% non-Hispanic white. Mean age was 15.0 years (range 8.7-18.5 years). Forty subjects (83%) were obese (mean BMI 96.1%). Mean 25-hydroxyviatmin D level was 47.4 nmol/L. The majority (97%) were vitamin D insufficient and 62% were vitamin D deficient. Correlation with BMI z-score was not significant. Vitamin D status did not vary by race.

Conclusions: Vitamin D deficiency is extremely common in a sun-rich environment among adolescents with type 2 diabetes, independent of BMI or race. Type 2 diabetes may be an added risk for vitamin D deficiency among obese, multiethnic children/adolescents even in a sun- rich environment.

To cite this article

Vitamin D status in children and adolescents with type 2 diabetes in a sun-rich environment

CellR4 2016; 4 (6): e2214

Publication History

Submission date: 07 Sep 2016

Revised on: 27 Sep 2016

Accepted on: 04 Oct 2016

Published online: 06 Dec 2016