Microfractured Lipoaspirate May Help Oral Bone and Soft Tissue Regeneration: a Case Report

CellR4 2015; 3 (3): e1583

  Topic: Regenerative Medicine     Category:

Abstract

Background: Among most of the mesenchymal stem cells sources, adipose tissue represents an ideal source because of the easy access and the simple isolation procedures. We developed an innovative technique (Lipogems®) to obtain micro-fragmented fat tissue transfer. This adipose tissue houses intact stromal vascular niche and mesenchymal stem cells with high regenerative capacity.

Objective: Aim of this case report is to show a novel Lipogems® application in a difficult case of oral surgery.

Materials and Methods: We treated a difficult patient with localized oral bone atrophy with Lipogems® micro fat grafting technique in combination with swine cortico-cancellous bone mix Gen-Os. The patient was followed-up for 12 months.

Results: As in other surgical applications, we observed an excellent tissue healing and absence of inflammation and infection, and a significant subjective pain reduction within the grafted areas. The postoperative radiographic evaluation and the histological slides showed homogeneous redefinition of bone defects, and intensive osteointegration.

Conclusions: This case report suggests that Lipogems® may improve the healing, osteointegration and stability of the implants in newly formed bone. More studies are required to confirm the efficacy of Lipogems® in oral surgery on larger scale.

To cite this article

Microfractured Lipoaspirate May Help Oral Bone and Soft Tissue Regeneration: a Case Report

CellR4 2015; 3 (3): e1583

Publication History

Published online: 28 May 2015