Favorable effects of omega-3 PUFAs on glucose control in an adolescent with type 1 diabetes using continuous glucose monitoring: a case report

CellR4 2020; 8: e2879
DOI: 10.32113/cellr4_20207_2879

  Topic: Autoimmunity, Diabetes, Nutrition     Category:

Abstract

Omega-3 polyunsaturated fatty acids (PUFAs) represent valuable dietary adjuncts for subjects with hypertriglyceridemia and at increased risk of cardiovascular disease, including subjects with type 1 diabetes (T1D). However, the exact role of omega-3 PUFAs in the regulation of glucose homeostasis and chronic complications in patients with diabetes remains uncertain. Herein, we report a 3-year follow-up of an athlete adolescent with T1D who started to use continuous glucose monitoring (CGM) two years after the diagnosis, and initiated omega-3 PUFA supplementation four years after the clinical onset of T1D. CGM metrics related to a 18-month period of omega-3 PUFA supplementation (50 mg/Kg/day of EPA and DHA) was compared to CGM metrics referring to a 18-month period prior to the nutrition intervention. Omega-3 PUFA supplementation resulted in a significant reduction of mean glucose and glucose variability, along with a significant increase in Time in range (TIR) 70-180 mg/dL. No significant changes were observed in daily insulin requirements between the two study periods. Future studies will be of assistance to better understand the exact impact of omega-3 PUFAs on the regulation of glucose homeostasis in patients with type 1 and its complications.

To cite this article

Favorable effects of omega-3 PUFAs on glucose control in an adolescent with type 1 diabetes using continuous glucose monitoring: a case report

CellR4 2020; 8: e2879
DOI: 10.32113/cellr4_20207_2879

Publication History

Submission date: 26 May 2020

Revised on: 01 Jun 2020

Accepted on: 26 Jun 2020

Published online: 14 Jul 2020