This review examines the current status of various cellular and non-cellular regeneration technologies used for the repair and regeneration of damaged connective tissue. The article explores the clinical use of bone marrow-derived mesenchymal stem cells, adipose tissue-derived mesenchymal stem cells, growth factors, cytokines, platelet-rich plasma and GOLDIC® method. To compare the regenerative capacity of these technologies, a systematic analysis of the regeneration quality is necessary, and a high-resolution magnetic resonance imaging (MRI) using a quality scoring system is needed. It is likely that in future clinical practice a combination of such technologies will offer the optimal treatment to patients with different connective tissue disorders, which must always be our ultimate goal.
To cite this article
The regeneration of damaged connective tissue: wishful thinking or reality?
Submission date: 07 Mar 2021
Revised on: 05 Apr 2021
Accepted on: 10 May 2021
Published online: 11 May 2021
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.